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Lesson 35 Certification Review Quiz

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Question 1 of 10

1. Question
B12 supplementation has been shown to reduce the severity of autoimmune conditions such as rheumatoid arthritis and eczema.
- a. True. Due to B12’s role in nitric oxide production, supplementation downregulates inflammatory processes mediated by iNOS.
- b. False. B12’s only role is as a cofactor for methionine synthase, which has no impact on autoimmunity.
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Question 2 of 10

2. Question
B12 deficiency symptoms can mimic what disease(s)?
- a. Respiratory conditions like asthma and COPD
- b. Those commonly associated with aging
- c. Type 2 diabetes
- d. All of the above
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Question 3 of 10

3. Question
Why is B12 deficiency missed in many patients?
- a. It’s not routinely tested by most physicians.
- b. There are no good tests for it, which means clinicians rely on symptoms for diagnosis.
- c. Conventional serum B12 tests measure the total amount of B12 in the blood, which does not rule out functional B12 deficiency.
- d. A & C
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Question 4 of 10

4. Question
What are other markers for B12 deficiency?
- a. MMA
- b. holoTC
- c. Homocysteine
- d. All of the above
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Question 5 of 10

5. Question
Overdiagnosis of B12 deficiency is innocuous, so extra testing has no negative health effects for patients.
- a. True. B12 is safe as a supplement, whereas if deficiency is missed, there can be irreversible neurological damage.
- b. False. B12 deficiency appears and manifests very quickly, so testing is unlikely to catch and prevent symptoms of deficiency.
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Question 6 of 10

6. Question
Which population(s) is at high risk for B12 deficiency?
- a. Crohn’s and celiac disease patients
- b. Chronic PPI users
- c. Vegetarians and vegans
- d. All of the above
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Question 7 of 10

7. Question
Why is it clinically relevant to know if a patient has pernicious anemia?
- a. They’ll have to supplement for the rest of their lives.
- b. They must have sublingual or IV B12 supplementation.
- c. It helps them take their B12 condition seriously and consistently supplement.
- d. All of the above.
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Question 8 of 10

8. Question
What supplement(s) is useful to take alongside B12?
- a. Betaine HCl
- b. Folate
- c. Calcium
- d. A & B
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Question 9 of 10

9. Question
What are the clinical signs of stage 4 vitamin B12 deficiency?
- a. Elevated homocysteine and urinary or serum methylmalonic acid (MMA)
- b. There are no clinical signs of B12 deficiency at this stage
- c. Signs and symptoms of B12 deficiency like macrocytic anemia and peripheral neuropathy or brain fog
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Question 10 of 10

10. Question
What is the maximum length of treatment for B12 supplementation?
- a. 6 months
- b. 1 year
- c. 3 months
- d. No maximum treatment length
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