Could you clarify how a single short-term incident of food poisoning would lead to long-term release of the anti-vinculin and anti-CdtB antibodies?

I don’t know the mechanisms intimately, but my understanding is that [for] the CdtB toxin that’s produced by the food poisoning, the body creates antibodies to target that toxin for removal, and then those antibodies cross-react with vinculin proteins in the small intestine. That only happens in a subset of people, not everybody, obviously, and I don’t know that we fully understand why it happens in that subset and not [in] other people after people.