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  4. This is a question about Cyrex Array 3 test results. The patient produced antibodies only to wheat IgG and IgA and wheat germ agglutinin. Based on this test result, should I ideally do both Arrays 2 and 4 or only 2? Interestingly, this man’s sister was recently diagnosed with type 1 diabetes.

This is a question about Cyrex Array 3 test results. The patient produced antibodies only to wheat IgG and IgA and wheat germ agglutinin. Based on this test result, should I ideally do both Arrays 2 and 4 or only 2? Interestingly, this man’s sister was recently diagnosed with type 1 diabetes.

Dr. Amy Nett: Array 2 is the intestinal permeability test, and Array 4 is the wheat and gluten cross-reactivity test, so it depends on what you’re looking for. Again, Chris and I rarely order the Array 2. That’s looking for intestinal permeability, but if what you’re wondering is how you can treat the gut, then the question is, is there dysbiosis, is there SIBO, is there yeast overgrowth, is there something that’s causing a leaky gut? My approach here would be if a patient has antibodies on Array 3, I would run Array 4 because I’m going to say this person has some intolerances to wheat and gluten—or at least to wheat—so are there other foods that they’re eating that are triggering them? The most common foods that they’re going to cross-react with or have sensitivities to are on Array 4, so I would run Cyrex Array 4, and then I would run gut testing—stool testing and SIBO breath testing plus or minus urine organic acids testing. That would be my approach to that. Again, let’s say the stool test and the SIBO breath test come back completely normal, the gut looks pristine, then I would run Array 2. Hopefully that helps you.

 

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