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  4. Looking for thoughts on a case of a 30-year-old female with hypothyroidism and non-celiac gluten sensitivity. She has improved significantly with Armour Thyroid and removing gluten but continues to complain of fatigue and brain fog. A stool study through Genova showed low diversity and 3+ growth of three different strains of yeast. Yeast isolated to the gut based on this exam and other tests. Just started boosting probiotics. She does not want to use nystatin.

Looking for thoughts on a case of a 30-year-old female with hypothyroidism and non-celiac gluten sensitivity. She has improved significantly with Armour Thyroid and removing gluten but continues to complain of fatigue and brain fog. A stool study through Genova showed low diversity and 3+ growth of three different strains of yeast. Yeast isolated to the gut based on this exam and other tests. Just started boosting probiotics. She does not want to use nystatin.

Dr. Amy Nett: Again, sort of when we talked about stool testing a few minutes ago, I don’t know if you want to rely exclusively on the Genova stool test. I’m not sure what other testing you’ve done, but I might consider additional testing through Doctor’s Data and BioHealth because, of course, yeast is a normal part of the GI tract. I can’t entirely tell, based on the history you’ve provided, whether or not this is actually yeast overgrowth because we do expect to see yeast in the GI tract. Again, that’s a completely normal part of the microbiome, but it’s all about balance. We don’t want overgrowth, but it’s not entirely clear, based on just the Genova test, if you can really tell whether or not that’s true yeast overgrowth.

If you did want to treat yeast, you could use something like Yeastonil, which is a product from Apex Energetics, and that specifically targets yeast. You could also look at the Byron White formula A-FNG. That’s also a little bit more specifically targeted to yeast. You could also include Lauricidin. That’s derived from coconut oil and has some antifungal properties. And maybe also include a biofilm disruptor in there, something like InterFase Plus if she tolerates eggs or Biofilm Defense if she tolerates dairy, but not eggs. You could do a protocol like that, certainly continue the probiotics, but again, I would make sure it’s really a yeast overgrowth. I’m not 100 percent sure if you want to rely on Genova alone, so hopefully you’ve done some other testing in there, but if you confirm it’s yeast overgrowth and you’re worried about the low diversity of bacteria, try maybe Yeastonil, A-FNG, and Lauricidin along with a biofilm disruptor.

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