Regarding eating high protein and having a history of kidney disease, if a person doesn’t know of family history, are there signs to look for once the person is off the high-protein diet that would be [a] red flag suggesting we cut back on protein?

Generally, people will know if they have kidney disease, but I mean, if they don’t, in terms of signs of kidney disease itself, I mean, the first thing is if you’re doing the comprehensive case review blood panel, you’re going to be looking, and of course, we’re going to talk about this when we get to the bloodwork, you’ll be looking at markers like BUN [blood urea nitrogen], creatinine, and eGFR [estimated glomerular filtration rate]. You’ll be looking at phosphorus. You’ll be looking at potassium. If any of those are off, then you can do follow-up testing like cystatin and other markers, which we’re going to discuss. Those are generally pretty sensitive to functional kidney problems, so they’ll be off. And then, with signs and symptoms, I’m sure many of the typical signs and symptoms of kidney disease, urine issues. You could see blood in the urine or foamy ear and/or the need to urinate more frequently, dry and itchy skin, trouble sleeping, fatigue, ankles and feet [that] are swollen, or have puffiness around the eyes that, of course, indicates an issue with fluid metabolism, so those are probably the most common ones that come to mind.