Chris Kresser: Well, the dosage that has been used in most studies is 4.5 milligrams, but almost every clinician that I know that works with LDN starts patients on a lower dose of maybe 1 to 1.5 milligrams. They stick with that for three to five days, maybe seven days if they’re having trouble, then go up to 3 milligrams, stick with that seven days, or longer if they’re having trouble adjusting, if they have insomnia or side effects like that, and then go all the way up to the 4.5 milligram dose. In my experience, I would say the majority of people end up settling at around 3 milligrams. We do see patients that end up using the full 4.5 milligram dose, but I would say 60 or 70 percent, if not more, end up on a lower dose, somewhere between 2 and 3 milligrams, so it really depends on the patient.