Have you had many clients with pyrrole disorder, and have you done much research on this and what drives it? If so, do you think it warrants high dosing continually, or is there a way of getting to the root cause of this?

Chris Kresser: That’s an interesting topic. As far as I can tell, there’s not really much good peer-reviewed research to support pyroluria and the whole constellation that has talked about regarding that on the Internet and from some integrative and functional doctors.