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Autoimmune Disorders

When discussing intestinal permeability, you showed a slide that listed a number of conditions associated with IP such as IBD, celiac, and other autoimmune diseases. I’m familiar with mechanisms connecting IP and these other conditions, and the connection makes a lot of sense. However, you also listed gastric ulcers as a symptom of intestinal permeability, and the mechanism behind that wasn’t clear to me. Can you explain how gastric ulcers could be a symptom of IP?

Chris Kresser: I think what happens with IAP is disruption of the gut microbiome, which, of course, could be a...

I have a client diagnosed with polychondritis of the ear. She came in months ago. I suggested food elimination and she disappeared. She is back now after beginning some food elimination. I suggested the Paleo reset and avoiding nightshades and eggs. What testing would you think of right away? She’s also very sympathetic nervous system type and was interested in what HPA testing you might suggest if you use one.

Yes, absolutely. Polychondritis of the ear, so uncommon chronic disorder of the cartilage that’s characterized by recurrent episodes of inflammation...

A 42-year-old female, normal weight, good general health. Five years ago, she had double vision in one of her eyes. About two weeks ago, she lost vision in the other eye. Both times she went to her ophthalmologist and was treated. The neuro-ophthalmologist recommended she see a multiple sclerosis specialist. She presented with a history of mild chronic constipation since childhood and chronic low hemoglobin levels. Other than that, she claimed to be a very healthy person, remarkable given the fact that as a child she lived in Belarus close to Chernobyl at the time of the disaster. I ordered general a general blood panel and SIBO test to begin my intervention. Gave her the 30-day Paleo reset and puzzled about what route to take regarding the radiation exposure and the possible effects on her health.

Dr. Amy Nett: Yes. Radiation exposure is a really difficult one because I don’t know how much can be done...

I have a patient with Hashimoto’s. Recently had lab work that came back with positive markers for rheumatoid arthritis. I haven’t actually seen the result. The patient has been on and off the autoimmune Paleo diet, has a difficult time adhering to it. Questions: Number one, do you know anything about ashwagandha and autoimmune disease? I see different ideas. It’s a nightshade so some practitioners say to stay off it.”

Dr. Amy Nett: Yes. I’m wondering what came back positive a little bit more specifically. That can be helpful because...

Any thought on melatonin and autoimmune disease? Again, I see different ideas depending on the practitioner.

Dr. Amy Nett: Good question. I don’t know that I’ve seen any contraindications to using melatonin in patients with an...
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