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Blood Chemistry

What are your favorite blood labs to screen for PCOS?

Dr. Amy Nett: I don’t even love the diagnosis of polycystic ovarian syndrome. PCOS here is polycystic ovarian syndrome. It’s...

On the CSAP, when secretory IgA is low, what does it mean? What should we be thinking possible causes are, and what are ways to bring up the sIgA levels?

Dr. Amy Nett: When I see a low secretory IgA, I definitely think about gut pathogens. That will include yeast...

Last week, you talked about secretory IgA and why it’s the last marker to normalize after treatment, but what I still don’t understand is why it’s sometimes very low or very high, and both abnormalities seem to indicate inflammation/pathology, but there doesn’t seem to be a more specific or consistent reason for this abnormality in one direction or the other. In last week’s gut case studies that Chris presented, the sIgA was almost always abnormal, but sometimes low and sometimes high. Why is this?

Dr. Amy Nett: This is a great question. At this point, I don’t think we know why sometimes it’s high...

Can you help me understand the implications of high thyroglobulin antibody level?

Chris Kresser: I’m going to answer this briefly, but I just want to remind everyone that we’re going to be...

I have run several Cyrex Array 3 panels where there are enough out-of-range results to request immunoglobulin panels. I would have suspected IgA deficiencies in these, which I have some idea how to address, but in these panels they are returning results showing low IgG and IgM. I’ve tried to find resources that are clinically useful in supporting these patients but have been unsuccessful. Do you have any input on the cause of IgG and IgM deficiencies and how to support these patients? It’s more of a general question, but if specific details are useful, here are the highlights.

Chris Kresser: The levels of IgG and IgM … Just for everyone listening, Holly gave me the exact values and...

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