Kresser Institute

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HPA Axis

How long do you typically put patients on the supplement plan for HPA dysregulation, and when do you typically retest?

Dr. Amy Nett: This depends a lot, I think, on the severity of the symptoms and what the underlying issue...

A little unclear on the physiology of a patient who has low free cortisol and low cortisone. Okay, so low free but on the higher end of metabolized cortisol.

Dr. Amy Nett: That sounds to me like a rapid clearance. That would be an increased clearance. If you have...

When we learned the HPA supplement protocols, there wasn’t a focus on duration of treatment. So when to stop the supplements in the near long term. I feel like this is kind of a black hole for me.

Dr. Amy Nett: Yeah, exactly. There is more to the question, so I’m going to come back to it. It’s...

Getting a little confused about cortisol, cortisone and all of the interrelations. Is there a chart or a book or an article that has these all on one page?

Dr. Amy Nett:  Yeah, there is. So a couple places—one, Precision Analytical has this amazing chart which I think we’ve...

Regarding cortisol-to-DHA ratios on the DUTCH test, approximately what ratio is considered normal and what is considered indicating catabolic or a high cortisol compared to the DHEA?

Dr. Amy Nett:  It’s a great question, because Chris talked about that this week on one of the presentations and...
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