Chris Kresser: There’s not really an ideal time of day, but if someone wants to make sure they’re in sustained ketosis, it would be good to test it at different times a day and after different activities or circumstances. Things like exercise can affect ketosis. Sleep can affect it. Obviously what you eat can affect it. It’s not a bad idea to test it in different circumstances. In terms of therapeutic range, that’s not an easy question to answer quickly. In general that range that you mentioned is the therapeutic range. I would say generally more like 0.7 and up I would consider therapeutic. Most people don’t need to go above two and certainly above three is not a good idea except in certain circumstances like someone who has severe epilepsy who might benefit from being in really deep ketosis. But as I discussed this with Robb Wolf in our seminar on ketogenic diets that we did in the ADAPT Academy, which I really recommend checking out if you haven’t already, in some cases people can experience really significant benefits of ketosis, even at the very low end of the range and below, like 0.5 to 0.7. Robb mentioned that that’s the range he’s usually in, and that can happen after you become significantly keto-adapted and your body doesn’t need to generate as many ketones to fulfill the function of the ketones because you’re so well keto-adapted. That can happen over time, and so if you see ketone production dropping over time, it’s not necessarily a bad thing. It could just mean that the patient has become more keto-adapted.