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Blood Sugar Disorders

Question about Metabolic Synergy. Metabolic Synergy was one of the supplements that we talked about in terms of, well, we talked really about the HPA axis and specifically talking a little bit more about blood sugar dysregulation. So when blood sugar is either high or low, you can use Metabolic Synergy and GlucoSupreme.I recently started a patient on Metabolic Synergy to help manage her blood sugar while we’re working on additional dietary tweaks. She has a history of obesity, hypertension, and hyperglycemia but has made a lot of diet and lifestyle changes and lost 70 pounds. Shortly after starting the Metabolic Synergy, she had an isolated episode of dizziness and heart palpitations. She was concerned she reacted to the green tea extract in the formula, although she also mentioned being dehydrated on this particular day. I’m wondering if you use this formula with caution in patients with hypertension that isn’t completely controlled and/or sensitivity to coffee. Would you recommend restarting it at a lower dose or switching to something without green tea extract?

Dr. Amy Nett:  So the green tea extract in Metabolic Synergy is actually decaffeinated. So there shouldn’t be any really...

Chris discussed berberine in the hyperglycemia section. Berberine is poorly absorbed, causes an overall reduction in the microbiome, and may reduce the overall diversity of the microbiome. For a patient with prediabetes or diabetes, do you think the benefit justifies the risk?

Dr. Amy Nett:  I think the question and what you need to put into context is you have a patient...

In the hyperglycemia section, Chris briefly discussed the True Health Diagnostics Diabetes Prevention and Management Panel but presented very little information on when to order the panel and nothing on how to interpret the results. Where do you suggest we find this information?

Dr. Amy Nett:  So the True Health Diagnostics panel I generally order either when I want additional markers on the...

The hyperglycemia content has referred a few times to ‘full-blown type 2 diabetes with beta cell destruction,’ and this seems slightly contrary to my understanding of the pathogenesis of most type 2 diabetics. My understanding is that insulin resistance inflammation and other functional mechanisms are much more common than hyperinsulinemia and beta cell destruction. We’ve seen some patients with beta cell destruction, but it is typically autoimmune with very low C-peptide and high Gad65 and or insulin antibodies. So similar to type 1 or LADA, the latent adult-onset diabetes, latent autoimmune diabetes of adulthood.

Dr. Amy Nett:  So, I think, okay. Interpreting this I think how I would piece this together is that I...

Follow-up to the diabetes question; can we tell the degree of beta cell destruction through the THD metabolic test?

Dr. Amy Nett:  Yeah, I think you can and Chris recommended the specific markers that come on that THD panel,...
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